Through the Lens of a Lead Discovery Scientist: Enabling Hit Identification Through DNA-Encoded Libraries
The phrase “you miss 100% of the shots you don’t take” was originally coined by Wayne Gretzky about scoring goals...
A Year of Driving Small Molecule Discovery
2022 was a big year here at X-Chem, so as we embark into 2023 it seems like a good time...
The 10th International Symposium on DNA-Encoded Chemical Libraries
Earlier this month I had the pleasure of attending the 10th International Symposium on DNA-Encoded Chemical Libraries (informally referred to...
New Directions in DEL Research
At X-Chem, we make it a priority to stay engaged with the latest advances in DNA-encoded library (DEL) technology and...
Solution DEL and Bead DEL: Two Tools for Advancing Drug Discovery
In 1992, the late professors Brenner and Lerner were the first to publish the concept of encoding synthetic chemistry with...
DELability – Protein Assessment for DEL Screening
Over the last 5 years, biopharma has fully embraced the use of DNA-encoded libraries (DELs) for hit identification for all...
Does Size Matter in DEL Screening?
One of the most attractive aspects of DNA-encoded library (DEL) technology is the vast number of compounds that can be...
X‑Chem’s New ReadiDELs Offer a Shorter Route to the Benefits of DEL Innovation
The last two years have seen X-Chem transform itself from a boutique DEL screening shop to an integrated drug discovery...
Getting Back to In Person
I recently had the pleasure of taking a trip to the West Coast to meet with several X-Chem clients. They...
A Track Record of Success
For those who didn’t notice, X-Chem underwent a major rebranding in mid-2021. We rolled out our new website, logo, color...